'''SPI Supplies DivisionStructure Probe, Inc.'''P.O. Box 656 West Chester, PA 19381-0656 USA'''Phone:''' 1-(610)-436-5400 '''Fax:''' 1-(610)-436-5755 [mailto:spi3spi@2spi.com spi3spi@2spi.com][http://www.2spi.com/ http://www.2spi.com]Manufacturer's CAGE: 1P573''' = Safety Data Sheet =
Date Effective: May 6, 2015
'''SPI # 02831-AA, 02831-NA SPI-Chem™ DBPComponent of SPI # 02808-AB, 02809-AB; Durcapan Resin Kit.Component of SPI # 02650-AB, 02650-AB; Araldite 6005 Kit. '''
== Section 1: Identification == Chemical Name/SynonymsDibutyl Phthalate Chemical familyEster Emergencies Contacting CHEMTREC: 24 Hour Emergency Use Only #'s... Worldwide phone: 1-(703)-527-3887 Worldwide FAX: 1-(703)-741-6090 Toll-free phone: 1-(800)-424-9300 USA only Product or Trade Name SPI-Chem™ DBP CAS #'s84-74-2 Dibutyl phthalate Chemical FormulaC6H4(CO2C4H9)2 '''GHS Classification(s):''' Reproductive toxicity Category 1B Acute aquatic toxicity Category 1 '''GHS Hazard Symbol(s)''' [[Image:]][[Image:]] '''Signal Word: '''Danger '''Hazard Statement(s):''' H360: May damage fertility or the unborn child H400: Very toxic to aquatic life '''Precautionary Statement(s):''' P201 Obtain special instructions before use. P273 Avoid release to the environment. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P501 Dispose of contents/ container to an approved waste disposal plant. Hazardous Material Information System USA Health2 Fire Hazard1 Reactivity0 Personal Protection NFPA Rating (estimated) Health2 Flammability1 Reactivity0 == Section 2: Composition == {| style="border-spacing:0;" | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| '''Components''' | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| '''RTECS #''' | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| '''CAS#''' | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| '''EINICS''' | style="border:0.05pt solid #000000;padding:0.0382in;"| '''Percent''' |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Dibutyl Phthalate | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| TI0875000 | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 84-74-2 | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 201-557-4 | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| 99 |} == Section 3: Hazard Identification == '''Emergency overview:''' May irritate skin, eyes, or respiratory tract. May cause harm to unborn children or impaired fertility. Very toxic to aquatic organisms '''Appearance:''' Colorless to light yellow liquid. '''Flash Point:''' 171° C (340° F) '''Method: '''closed cup '''Danger''' '''Route of Exposure: '''skin contact, skin absorption, eye contact, inhalation, ingestion '''Target Organs:''' kidneys, liver, lungs, testes, central nervous system, eyes '''Potential Health Effects''' '''Skin contact:''' causes skin irritation '''Skin absorption:''' May be harmful if absorbed through the skin '''Eye contact:''' causes eye irritation '''Inhalation:''' May be harmful if inhaled. Vapor or mist is irritating to the mucous membranes and upper respiratory tract. '''Ingestion:''' May be harmful if swallowed '''Chronic:''' Chronic exposure may effect reproductive system, with potential risk of harm to unborn children. Animal testing has found results of reduced testes weights and histological evidence of testicular injury. '''Signs and Symptoms of Exposure:''' Nausea, dizziness, and headache. To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. == Section 4: First Aid Measures == '''Eyes:''' Upon contact, wash eyes thoroughly with copious amounts of warm water for at least 15 minutes, holding the eyes open. Remove contacts if present. Seek medical attention. '''Skin:''' Wash contaminated area thoroughly with soap and water. Remove contaminated clothing and launder before reuse. Cover contaminated skin with an emollient. If irritation persists, seek medical attention. '''Ingestion:''' Upon ingestion, dilute with 2-4 glasses of water. Do not induce vomiting and seek medical attention. '''Inhalation:''' Remove victim to fresh air. If irritation persists, seek medical attention. If victim is not breathing, administer oxygen. '''Notes to Physician:''' Treat supportively and symptomatically. == Section 5: Fire Fighting Measures == '''General Information:''' Always wear full protective equipment including self containing breathing apparatus. '''Auto Ignition Temperature:''' 402° C (755.6° F). '''Flash Point:''' 171° C (340° F, CC). '''Explosion Lower Limit: '''0.47% '''Flammability:''' May be combustible at high temperatures. '''Hazardous Combustion Products:''' Carbon monoxide, carbon dioxide. '''Unusual Fire/Explosion Hazards:''' N/A '''Extinguishing Media:''' For small fires, use dry chemical. For large fires, use water spray, fog, or foam. Do not use water jets. '''Protective Measures:''' No special protective measures are required. == Section 6: Accidental Release Measures == '''Spills/Leaks:''' Wear appropriate protective equipment. Contain the spill. Soak up spill with absorbent material and place in appropriate disposal container. '''Disposal Procedure:''' Dispose of in accordance with all local, state, and federal environmental regulations. == Section 7: Handling and Storage == '''Handling:''' Always wear protective equipment appropriate to the task. Avoid contact with skin, eyes, and clothing. Always use adequate ventilation, avoiding breathing fumes or mists. Launder contaminated clothing before reuse. Keep away from flames, sources of ignition, and incompatible materials (oxidizing agents, acids, and alkalies). '''Storage:''' Store closed containers, in well-ventilated, cool areas. Keep out of the reach of children. == Section 8: Exposure Controls and Personal Protection == '''Engineering Controls:''' Exhaust ventilation should be available to keep concentrations below T.L.V. Shower and eye wash stations should be readily accessible in work area. = Personal Protective Equipment = '''Eyes:''' Chemical safety goggles or glasses with side shields are required. '''Skin:''' Wear chemical resistant gloves to prevent skin contact. '''Clothing:''' Protective clothing such as long sleeves or a lab coat should be worn. When handling heated materials, also be sure to use heat-resistant gloves, boots and face protection. '''Respirators:''' If exposure limit is reached, a respirator that conforms to OSHA's 29 CFR 1910.134 and ANSI Z88.2 or (European Standard EN 149) requirements should be used. {| style="border-spacing:0;" | colspan="4" style="border:0.05pt solid #000000;padding:0.0382in;"|
'''Exposure Limits'''
|- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"|
'''Component'''
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'''ACGIH'''
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'''NIOSH'''
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'''OSHA - Final PELs'''
|- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Dibutyl Phthalate | style="border:0.05pt solid #000000;padding:0.0382in;"| 5 mg/m3 (TWA) | style="border:none;padding:0.0382in;"| 5 mg/m3 (TWA) | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| 5 mg/m3 (TWA) |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:none;border-right:none;padding:0.0382in;"| 4000 mg/m3 (IDLH) |} == Section 9: Physical and Chemical Properties == '''Physical State:''' Liquid. '''Appearance:''' Colorless to light yellow liquid. '''Odor:''' Odorless. '''pH:''' N/A '''Vapor Pressure:''' 0.00007 mm Hg @ 25° C. '''Vapor Density:''' 9.6 (air = 1). '''Evaporation Rate:''' 0 (butyl acetate = 1) '''Viscosity:''' 21 cps @ 20° C '''Boiling Point:''' 340° C '''Freezing/Melting Point:''' -35° C '''Autoignition Temperature:''' 402° C (755.60° F) '''Flash Point:''' 171° C (CC). '''Decomposition Temperature:''' N/A '''Explosion Limits''' Lower: 0.47% Upper: N/A '''Solubility in water:''' Insoluble. '''Specific Gravity/Density:''' 1.043 (water = 1). '''Molecular Formula:''' C6H4(CO2C4H9)2 '''Molecular Weight:''' 278.34 amu. '''Refractive Index: '''1.492 == Section 10: Stability and Reactivity == '''Chemical Stability:''' Stable under normal handling and working conditions. '''Conditions to Avoid:''' Excessive heat. '''Incompatibility with Other Materials:''' Strong oxidizing agents. Strong acids. Strong bases, Nitrates, Chlorine '''Hazardous Decomposition of Products:''' Carbon oxides. Acrid smoke. Fumes. '''Hazardous Polymerization:''' Will not occur. == Section 11: Toxicological Information == '''Route of Exposure''' '''Skin contact:''' Causes skin irritation '''Skin absorption:''' May be harmful if absorbed through the skin '''Eye contact: '''Causes eye irritation '''Inhalation:''' May be harmful if inhaled. Vapor or mist is irritating to the mucous membranes and upper respiratory tract. '''Ingestion: '''May be harmful if swallowed. '''Target Organs or systems:''' kidneys, liver, lungs, testes, central nervous system, eyes '''Sings and symptoms of exposure: '''Exposure can cause nausea, dizziness and headache. To the best of our knowledge, the chemical, physical, and toxicological properties have not be thoroughly investigated. '''Toxicity data''' {| style="border-spacing:0;" | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Species | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Test | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Route of Application | style="border:0.05pt solid #000000;padding:0.0382in;"| Dose |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Rat | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| LD50 | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Oral | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| 8000 mg/kg |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Rat | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| LC50 | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Inhalation | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| 4250 mg/m3 |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Rat | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| LD50 | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Intraperitoneal | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| 3050 ul/kg |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Rat | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| LD50 | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Intramuscular | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| >8 mg/kg |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Mouse | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| LD50 | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Oral | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| 5289 mg/kg |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Mouse | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| LC50 | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Inhalation | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| 25,000 mg/m3 |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Mouse | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| LD50 | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Intraperitoneal | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| 3570 mg/kg |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Mouse | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| LD50 | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Intravenous | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| 720 mg/kg |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Rabbit | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| LD50 | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Skin | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| >20 ml/ kg |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Guinea pig | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| LD50 | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Oral | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| 10000 mg/kg |} '''Chronic Exposure- Teratogen''' '''Result: '''May cause congenital malformation in the fetus {| style="border-spacing:0;" | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Species | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Dose | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Application | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Exposure Time | style="border:0.05pt solid #000000;padding:0.0382in;"| Result |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Rat | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 2520 mg/kg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Oral | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 1-21D preg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| Extra embryonic structures |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Rat | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 1500 mg/kg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Oral | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 15D preg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| Abnormalities: Craniofacial and musculoskeletal Embryo/fetus: fetotoxicity (except death) |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Rat | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 305 mg/kg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Intraperitoneal | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 5-15D preg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| Embryo/fetus: fetotoxicity (execpt death) Abnormalities: musculoskeletal |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Mouse | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 8640 mg/kg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Oral | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 1-18D preg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| Embryo/fetus: fetotoxicity (except death) |} '''Chronic Exposure – Mutagen''' {| style="border-spacing:0;" | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Species | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Dose | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Cell Type | style="border:0.05pt solid #000000;padding:0.0382in;"| Mutation Test |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Human | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 354 mmol/l | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| lymphocyte | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| DNA damage |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Human | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 354 mmol/l | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Other cell types | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| DNA damage |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Hamster | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 30 mg/l | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| fibroblast | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| Cytogenetic analysis |} '''Chronic Exposure – Reproductive Hazard''' '''Result:''' Overexposure may cause reproductive disorders based on test with laboratory animals {| style="border-spacing:0;" | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Species | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Dose | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Application | style="border-top:0.05pt solid #000000;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"|
Exposure Time
| style="border:0.05pt solid #000000;padding:0.0382in;"| Result |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Rat | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 24 gm/kg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Oral | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 20D male | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| Paternal: testes, epididymis, sperm duct Paternal: spermatogenesis |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Rat | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 6750 mg/kg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Oral | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 0-8D preg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| Maternal: Uterus, cervix, vagina Fertility: Post implantation mortality |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Rat | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 2250 mg/kg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Oral | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 7-9D preg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| Abnormalities: Craniofacial Embryo/fetus: fetotoxicity Fertility: Post implantation mortality |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Rat | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 8820 mg/kg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Oral | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 7-15D preg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| Fertility: Post implantation mortality Embryo/fetus: fetotoxicity/fetal death |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Rat | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 19 gm/kg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Oral | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 3-22D preg 2-20D post | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| Newborn: Delayed effects, physical Maternal: uterus, cervix, vagina |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Rat | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 6750 mg/kg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Oral | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 0-8D preg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| Fertility: litter size, post implantation mortality Maternal: other effects |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Rat | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 1017 mg/kg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Intraperitoneal | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 5-15D preg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| Fertility: Post-implantation mortality |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Rat | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 6 gm/kg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Intraperitoneal | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 3-9D preg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| Newborn: weaning or lactation index |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Mouse | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 7200 mg/kg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Oral | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 1-18D preg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| Abnormalities: Central nervous system Fertility: litter size, post-implantation mortality |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Mouse | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 20 gm/kg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Oral | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 6-13D preg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| Fertility: litter size |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Mouse | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 16800 mg/kg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Oral | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 7D male | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| Paternal: testes, epididymis, sperm duct |- | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Guinea pig | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 14 gm/kg | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| Oral | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:none;padding:0.0382in;"| 7D male | style="border-top:none;border-bottom:0.05pt solid #000000;border-left:0.05pt solid #000000;border-right:0.05pt solid #000000;padding:0.0382in;"| Paternal: testes, epidiymis, sperm duct |} *post-implantation mortality-dead and/or resorbed implants per total number of implants *Fetotoxicty- except death e.g. stunted fetus unless otherwise specified *Weaning or lactation index- e.g. number alive at weaning per number alive at day 4 == Section 12: Ecological Information == '''Exotoxicity''' '''Species''' '''Bluegill/Sunfish''' 1.2 mg/L; 96H '''Fathead Minnow (fish)''' 1.3 mg/L; 96H '''Environmental Fate:''' This product is expected to have low mobility in soil. '''Aquatic:''' This product is expected to adsorb to suspended solids and sediments in water. Expected to volatilize from water surfaces. In high concentrations, this product is dangerous to aquatic life. '''Atmospheric:''' This product is expected to exist in particulate and vapor phases in the atmosphere, with a half-life of 42 hours. == Section 13: Disposal Considerations == '''Waste Disposal:''' Dispose of in accordance with all local, state, and federal environmental regulations. '''RCRA P-Series:''' None. '''RCRA U-Series:''' Waste number U069 == Section 14: Transport Information == '''US DOT Hazard Class:''' Shipping Name: Environmentally Hazardous Substances, Liquid, N.O.S. Hazard Class: 9 UN # 3082 Packing Group: III Additional Information: None. [[Image:]][[Image:]] '''Canada TDG:''' Shipping Name: Environmentally Hazardous Hazard Class: 9 UN # 3082 Packing Group: III Additional Information: Substances, Liquid, N.O.S. == Section 15: Regulatory Information == '''United States:''' '''TSCA''' All ingredients are on the TSCA inventory or are not required to be listed on the TSCA inventory. '''SARA''' '''Section 302 (RQ)''' Not listed '''Section 302 (TPQ)''' Not listed '''SARA 311/312''' chronic health hazard '''Section 313''' Dibutyl phthalate 84-74-2 '''States''' '''Massachusetts Right To Know:''' Dibutyl phthalate 84-74-2 '''Pennsylvania Right To Know:''' Dibutyl phthalate 84-74-2 '''New Jersey Right To Know: '''Dibutyl phthalate 84-74-2 '''California Prop. 65: '''Dibutyl phthalate 84-74-2 '''CANADA:''' CAS# 26142-30-3 is listed on the DSL List. '''WHMIS''' This product is not a Controlled Product under WHMIS. '''European Directives Classification''' '''Hazard Symbol(s)''' [N] Dangerous for the environment [T] Rep Cat 2 [T] Rep Cat 3 '''Risk Phrase(s):''' R61: May cause harm to the unborn child. [T] Rep Cat 2 R50: Very toxic to aquatic organisms. [N] R62: Possible risk of impaired fertility. [T] Rep Cat 3 '''Safety Phrase(s):''' S53: Avoid exposure - obtain special instructions before use. S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). S61: Avoid release to the environment. Refer to special instructions/Safety data sheets. '''WGK (Dibutyl phthalate CAS# 84-74-2):''' 3 == Section 16: Other Information == '''Disclaimer of Liability:''' Caution! Do not use SPI Supplies products or materials in applications involving implantation within the body; direct or indirect contact with the blood pathway; contact with bone, tissue, tissue fluid, or blood; or prolonged contact with mucous membranes. Products offered by SPI Supplies are not designed or manufactured for use in implantation in the human body or in contact with internal body fluids or tissues. SPI Supplies will not provide to customers making devices for such applications any notice, certification, or information necessary for such medical device use required by US FDA (Food and Drug Administration) regulation or any other statute. SPI Supplies and Structure Probe, Inc. make no representation, promise, express warranty or implied warranty concerning the suitability of these materials for use in implantation in the human body or in contact with internal body tissues of fluids. The information and recommendations set forth above are taken from sources believed to be accurate as of the date hereof, however SPI Supplies and Structure Probe, Inc. make no warranty with respect to the accuracy of the information or the suitability of the recommendations, and assume no liability to any user thereof. The information contained in this sheet does not constitute a hazard assessment and should not be used in place of the user's own assessment of work place risks as required by other health and safety legislation. Be aware of the Structure Probe, Inc. [http://www.2spi.com/copyright.html Copyright Policy]. Structure Probe, Inc. grants a nonexclusive license to make unlimited copies of this safety sheet for internal use only. Quite obviously, this information would pertain only to this material when purchased from SPI Supplies as product from other sources, with other ingredients and impurity levels could have substantially different properties.