SPI Supplies SPI-Chem™ SPI Supplies Division
Structure Probe, Inc.

P.O. Box 656 West Chester, PA 19381-0656 USA
Phone: 1-(610)-436-5400 Fax: 1-(610)-436-5755
E-mail: spi3spi@2spi.com

WWW: http://www.2spi.com
Manufacturer's CAGE: 1P573

Material Safety Data Sheet

SPI #02820-DA, 02820-MB, 02820-AF 3-Aminopropyltriethoxysilane

Section 01 Identification

Date Effective......... January 7, 2011 
                        (most recent revision)

Chemical Name/Synonyms. 3-Aminopropyltriethoxysilane

Emergencies             Contacting CHEMTREC 24 Hour Emergency 
Use Only #'s........... Worldwide phone : 1-(703)-527-3887
                        Worldwide FAX   : 1-(703)-741-6090
                        Toll-free phone : 1-(800)-424-9300 USA only

Product or Trade Name....  SPI# 02820-DA, 02820-MB, 02820-AF APTES
Synonyms.................  3-Aminopropyltriethoxysilane; (gamma-Aminopropyl)triethoxysilane; 
                           Propylamine,3-(triethoxysilyl)-; Silane, gamma-aminopropyltriethoxy-; 
                           Triethoxy(3-aminopropyl)silane; 3-(Triethoxysilyl)propylamine.

Hazardous Material
Information System
Health 3 National Fire
Protection Association
Fire Hazard 1
Reactivity 1
Personal Protection 0
NFPA Rating: Health: 3; Flammability: 1; Reactivity: 1 HMIS Rating: Health: 3; Flammability: 1; Reactivity: 1

Section 2 Composition

Component Name   	CAS #	 Concentration     EINECS/ELINCS
			919-30-2	>97%		213-048-4
Ethanol			64-17-5	

*EC Annex I Index# 612-108-00-0	<1%		200-578-6

Section 3: Hazard Identification

Emergency overview:  Harmful if swallowed. Corrosive. Material is extremely destructive to tissue 
of the mucous membranes and upper respiratory tract, eyes, and skin.

Appearance: Clear, colorless liquid
Flash Point: 98°C (208°F) 

Warning! Harmful by ingestion, Corrosive

Target Organs: Nerves, Liver, Kidney
Potential Health Effects
Eye: Vapors may cause immediate or delayed severe eye irritation.  Liquid can cause severe 
conjunctivitis and corneal damage.

Skin: Causes skin burns.  May be harmful if absorbed through skin.
Ingestion: Harmful if swallowed.  Causes burns.
Inhalation: Harmful if inhaled.  May cause respiratory tract irritation.  Corrosive 
material  extremely destructive to the tissue of the mucous membranes and the upper respiratory 
tract.  May cause spasm, inflammation and edema of the bronchi, pneumonitis, pulmonary edema, 
burning sensation, cough, wheezing, laryngitis, shortness of breath, headache, nausea, vomiting.

Section 4: First Aid Measures

Eyes: In case of contact, immediately flush eyes with flowing water for at least 15 minutes.  
Separate eyelids with fingers.  Seek medical attention.

Skin:  Flush with copious amounts of water for 15 minutes, then wash with soap and water. 
Remove contaminated clothing & shoes.  Seek medical attention.

Ingestion: If swallowed, wash out mouth with water, provided person is conscious.  Do not 
induce vomiting.  Seek immediate medical attention.

Inhalation:  If inhaled, remove to fresh air.  If not breathing give artificial respiration.  
If breathing is difficult, give oxygen.

Section 5: Fire Fighting Measures


General Information:
Under fire conditions, material may decompose to forma flammable and/or explosive mixtures. 
Emits toxic fumes under fire conditions.

Flash point: 98°C (208°F) 

Autoignition temperature: Not available

Explosion limits:
	Upper: 4.5%
	Lower: 0.8%

Extinguishing Media: Alcohol-resistant foam, carbon dioxide, dry chemical.

Special Fire Fighting Procedures: Avoid eye and skin contact.  Wear self-contained 
breating apparatus if necessary; do not breathe fumes or inhale vapors.

Section 6: Accidental Release Measures


General Information: Evacuate personnel to safe area.  Avoid breathing vapors, mist or gas. 
Ensure adequate ventilation.Wear self-contained breathing apparatus, rubber boots, and heavy 
rubber gloves.

Spills/Leaks: Do not let product enter drains.  Cover with inert material such as dry lime 
or soda ash, pick up, keep in a closed container, and hold for waste disposal.  Ventilate area and 
wash spill site after material pickup is complete.

Section 7: Handling and Storage

Handling: Do not breathe vapor.  Do not get in eyes, on skin, or on clothing.  
Avoid prolonged or repeated exposure.

Storage: Keep container tightly closed in a dry, well ventilated area. Store 
under inert gas  moisture sensitive. 

Section 8: Exposure Controls and Personal Protection

Engineering Controls: Safety shower and eye bath.  Use only in a 
chemical fume hood.

Exposure Limits: None known.

Personal Protective Equipment

Eyes: Chemical splash goggles.
Skin: Rubber, neoprene or nitrile gloves.
Clothing: Appropriate to avoid skin contact. Launder before reuse.
Respirators: Where risk assessment shows air-purifying respirators are appropriate, 
use a full-face respirator with multi-purpose comination (US) for typoe ABEK (EN14387) 
respirator cartridges as a backup to engineering controls.

Section 9: Physical and Chemical Properties

Physical State:  Liquid
Appearance:  Clear, colorless
Odor:  ammonia-like
pH:  Not available
Vapor Pressure:  10mm at 100°C
Vapor Density:  (air=1): >1
Evaporation Rate:  (butyl acetate =1): <1
Viscosity:  Not available
Boiling Point:  213-216C (415-421F)
Freezing/Melting Point:  Not available 
Autoignition Temperature:  Not available
Flash Point:  98°C (208F)
Decomposition Temperature:  Not avaliable
Explosion Limits:
	Lower:  0.8%
	Upper:  4.5%
Solubility in water: Not available

Specific Gravity/Density: 0.949g/cm3
Molecular Formula:  C9H23NO3Si
Molecular Weight:  221.37

Section 10: Stability and Reactivity

Chemical Stability: Stable
Conditions to Avoid: May decompose on exposure to moist air or water.
Incompatibility with Other Materials: Strong oxidizing agents.
Hazardous Decomposition of Products: Carbon monoxide, carbon dioxide, nitrogen 
oxides, silicon oxide.
Hazardous Polymerization:  Will not occur.

Section 11: Toxicological Information

RTECS#:   TX2100000
CAS#:   919-30-2

LD50/LC50 Information: 
	Oral			Rat	1780 mg/kg
	Oral			Mouse	4000 mg/kg	
	Intraperitoneal		Mouse	260 mg/kg
	Skin			Rabbit	4 mg/kg
	Oral			Mammal	4000 mg/kg
Irritation Information: 
	Skin		Rabbit	01.mg/24H 	Open irritation test
	Skin		Rabbit	5mg/24H 	Severe irritation effect
	Eyes		Rabbit	100 mg		Mild irriation effect
	Eyes		Rabbit	0.75 mg/24H 	Severe irritation effect
Carcinogenicity:  Not known

California Prop 65 Components:  This product does not contain any chemicals know 
to the State of California to cause cancer, birth, or any other reproductive defects.

No component of this product present at levels greater than or equal to 0.1% is identified 
as probable, possible or confirmed human carcinogen. 

Teratogenicity:  Not known.
Reproductive Effects:  Not known.
Neurotoxicity:   Not known.
Mutagenicity:   Not known.
Other Studies:   Not known.

Section 12: Ecological Information

Exotoxicity: Not available.
Environmental Fate: Not available.
Aquatic: May be hazardous to aquatic life if released to open waters.
Atmospheric: Not available.
Physical:  Not available.

Section 13: Disposal Considerations

Contact a licensed professional waste disposal service to dispose of this material. 
Dissolve or mix the material with a combustible solvent and burn in a chemical 
incinerator equipped with an afterburner and scrubber.  Contaminated packaging shoudlbe 
disposed of as unused product.  Observe all federal, state and local environmental 

Section 14: Transport Information

US DOT Hazard:

UN Number: UN3267
DOT Shipping Name:  Corrosive Liquid, Basic Organic, N.O.S. 

DOT Hazard Class: 8
Packing Group: III
DOT Labels: Corrosive

IATA (for international shipments)

UN Number: UN3267
IATA Shipping Name:  Corrosive Liquid, Basic Organic, N.O.S. 

IATA Hazard Class: 8
Packing Group: III
IATA Labels: Corrosive
Marine Pollutant: No

Section 15: Regulatory Information

United States:

All components of this product are on the TSCA Inventory.


Section 302:
No component of this product is subject to the reporting requirements of SARA 
TitleIII, Section 302. 

Section 311/312:
Acute Health Hazard, Chronic Health Hazard

Section 313:
No component of this product is present in levels that exceed the threshold (De Minimis) 
reporting levels established by SARA Title III, Section 313.

Target Organ Effect, Harmful by ingestion, Corrosive

State (Individual states in the USA):
Listed  by New Jersey and Pennsylvania as a Right to Know Component.

California No Significant Risk Level: 
Not listed.
California Prop. 65:
Not listed.

European/International Regulations:
European Labeling in Accordance with EC Directives

Hazard Symbols: Xn, C
Risk Phrases:        
	R22	Harmful if swallowed
	R34	Causes Burns

Safety Phrases:
	S1/2		Keep locked up and out of the reach of children
	S26		In case of contact with eyes, rinse immediately with plenty of water and seek 
  medical advice 
  S36/37/39	Wear suitable protective clothin, gloves and eye/face protection 
	S45		In case of accident of if you feel unwell, seek medical advice immediately 
  (show the label where possible)

WGK (Water Danger/Protection):
CAS# 919-30-2: 1

Switzerland:  Poison Class: 4

CAS# 919-30-2 is listed on the DSL List.
This product has a WHMIS classification of E, D1B.

Section 16: Other Information

If this product should be used in ways that are outside of the intended applications in 
scanning electron microscope laboratories, and if it is going to be formulated into some 
other system, so that it becomes just another component of that other system, read the 
MSDS sheets for the other components before blending as the resulting mixture may have 
the hazards of all of its parts.

Disclaimer of Liability:

Caution!  Do not use SPI Supplies products or materials in applications 
involving implantation within the body; direct or indirect contact 
with the blood pathway; contact with bone, tissue, tissue fluid, or 
blood; or prolonged contact with mucous membranes.  Products offered 
by SPI Supplies are not designed or manufactured for use in implantation 
in the human body or in contact with internal body fluids or tissues.  
SPI Supplies will not provide to customers making devices for such 
applications any notice, certification, or information necessary for 
such medical device use required by US FDA (Food and Drug Administration) 
regulation or any other statute. SPI Supplies and Structure Probe, Inc. 
make no representation, promise, express warranty or implied warranty 
concerning the suitability of these materials for use in implantation 
in the human body or in contact with internal body tissues of fluids.


  The information and recommendations set forth above are taken from 
  sources believed to be accurate as of the date hereof, however SPI 
  Supplies and Structure Probe, Inc. make no warranty with respect to the 
  accuracy of the information or the suitability of the recommendations, 
  and assume no liability to any user thereof. The information contained 
  in this sheet does not constitute a hazard assessment and should not be 
  used in place of the user's own assessment of work place risks as 
  required by other health and safety legislation.

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