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Structure Probe, Inc.

P.O. Box 656 West Chester, PA 19381-0656 USA
Phone: 1-(610)-436-5400 Fax: 1-(610)-436-5755
E-mail: spi3spi@2spi.com

WWW: http://www.2spi.com
Manufacturer's CAGE: 1P573

Material Safety Data Sheet

SPI #02587-AB Methylene Blue 1 % Solution in Water

Section 01: Identification

Date Effective... January 8, 2009
              (most recent revision)


Chemical Name/Synonyms...
        3,7-Bis(dimethylamino)phenothiazin-5-ium
		Chloride in Water
	Basic Blue 9
	C.I. 52015

Chemical Family...  Not known


Emergencies 
Use Only #'s:

Contacting CHEMTREC 24 Hour Emergency 
Worldwide phone : 1-(703)-527-3887
Worldwide FAX   : 1-(703)-741-6090
Toll-free phone : 1-(800)-424-9300 USA only

Product or Trade Name....  SPI #02587-AB Methylene Blue 1% in Water
						Solution

CAS #....................7732-18-5 Water
Chemical Formula .......  H2O

CAS #....................  7220-79-3 Methylene Blue
Chemical Formula.........  C16H18CIN3S.3H2O

Hazardous Material
Information System
USA
Health 0 National Fire
Protection Association
USA
Fire Hazard 0
Reactivity 0
Personal Protection  
NFPA (National Fire Protection Association) Rating (Scale 0-4) : (estimated) Health 0 Flammability 0 Instability 0


Section 02: Composition information on Ingredients

Component	CAS#		%		EINECS		RTECS
Water		7732-18-5	99		231-791-2	AO0110000
Methylene blue	7220-79-3	1		200-515-2	SP5740000



Section 03: Hazards Identification

Emergency overview:
       This material is not hazardous by OSHA Hazard Communication 
       Definition.

Signal Word(s):
       Harmful!  Irritant!

Main Hazards:
       Harmful by inhalation, in contact with skin, and if swallowed.  Irritating
       to eyes, respiratory system and skin.
       

Physical Health Hazards:
       Dry dust may form respirable particulates if disturbed.  
       If this material gets into the eyes, it could be irritating.
       Material could be irritating if the dust is inhaled.  Could
       also be irritating if skin is exposed to the dry powder.

Physical state:   Liquid

Color:            blue

Odor:             None

Odor threshold:   No data available

Potential Health Effects:

Routes of exposure:
      Eye contact, ingestion, skin contact

Signs and Symptoms of Acute Exposure:
	This material if used properly, should not pose any kind of real
	hazard. If the material is used improperly, for example, if the
	dust is inhaled, it could be very irritating to the respiratory
	tract.

Eye contact:
        Mechanical irritation is possible; can be irritant.

Skin Contact:
	There may be irritation and redness at the site of contact.

Ingestion:
	May be harmful if swallowed. Nausea and stomach pain may occur.
	There may be vomiting and diarrhea. Headaches or general malaise
	may result.  May cause blueness around the mouth.

Inhalation:
	Exposure may cause coughing or wheezing.  May cause blueness
	around the mouth.  Nausea and stomach pain may occur.




Section 04: First Aid Measures


Take proper precautions to ensure your own health and safety before 
attempting to rescue and providing first aid.  For specific information 
refer to the Emergency Overview in Section of this MSDS.

Symptoms:


Skin contact:
There may be irritation and redness at the site of contact.  An itchy
      rash may occur at the site of contact.

Eye contact:
There may be irritation and redness.  

Ingestion:
Nausea and stomach pain may occur.  There may be vomiting.

Inhalation:
Nausea and stomach pain may occur.


Action:


Skin Contact:
Remove all contaminated clothes and footwear immediately unless stuck
      to skin.  Drench the affected skin area with running water for
      ten minutes or longer if substance is still on skin.  Transfer
      to hospital if there are burns or symptoms of poisoning.

Eye Contact:
Wash eyes with clean low-pressure water.  Continue to rinse for 15
      minutes. Seek medical advice for examination and possible
      further treatment of the affected eye(s).

Ingestion:
Do not induce vomiting. Wash out mouth with water.  Seek emergency
      medical attention at once.
           
Inhalation:
Remove victim from further exposure ensuring your own safety first. If
      unconscious,  and check for breathing and apply artificial
      respiration if necessary.  If breathing becomes bubbly, have the
      casualty sit and provide oxygen if available.If unconscious and
      breathing is OK, place in the recovery position.  If conscious,
      ensure the victim sits or lies down.  Seem medical attention at once.



Section 05: Fire Fighting Measures


Extinguishing Media:
Any suitable medium for extinguishing the supporting fire.  Use water to
      keep fire-exposed containers cool.  For fire specifically involving
      this product, use water spray, dry chemical powder, alcohol or
      polymer foam,  or CO2 to extinguish the fire.

Exposure Hazards:
In combustion emits toxic fumes.

Protection of Fire-Fighters:

Protective Equipment/Clothing:
Wear a NIOSH approved positive pressure self-contained breathing apparatus
      and firefighter turnout gear.  This should be selected on the basis
      of the supporting fire.  Avoid having the fumes come in contact with
      skin and eyes.





Section 06: Accidental Release Measures


See Sections 8 and 13.

Personal precautions:
Do not attempt to take action without suitable protective clothing.
      Do not create dust so that there are air borne particulates that
      could be inhaled.

Environmental precautions:
Do not discharge into drains, rivers, or lakes.

Release response:
Pick up with dry cloth and retain for recycle or disposal.  Do not flush
      spilled material to the sewer or the environment.  Waste materials
      should be put into a labeled disposal container for disposal
      according to local regulations.




Section 07: Handling and Storage


Handling:
Use in well ventilated areas.  Wear suitable gloves if prolonged exposure
      is contemplated.  Avoid direct contact with the material.

Storage:
Store away from excessive heat and generally in a cool dry place.  Keep
      container tightly closed.  Keep away from direct sunlight.  Avoid contact
      with water or humidity.





Section 08: Exposure Controls and Personal Protection

Engineering measures:
Ensure that there is mechanical ventilation of the area.

Respiratory protection:
Respiratory protective device with particle filter class P2S (EN143).
      Self-contained breathing apparatus must be available in case of emergency.

Hand protection:
Protective gloves

Eye protection:
Safety goggles.  Ensure eye bath is readily available.

Skin protection:
Protective clothing with elastic cuffs and closed neck.  Boots should
      be made of PVC.


The product does not present a significant hazard in normal laboratory
      use as a light microscope stain.  The data provided above refer
      to prolonged contact with large quantities of product.



Section 09: Physical and Chemical Properties


Boiling Point/Range:     100F

pH:                      Not applicable

Vapor Pressure:          14 mm Hg

Viscosity:               Not applicable

Specific Gravity: 
     Solid/Liquid        Not known

Water solubility:        Soluble
Ethanol solubility:      Soluble

Octanol/Water Partition Coefficient in Kow:  Specific value not known

Melting/Freezing Point:  0F

Evaporation Rate:        Not applicable

Odor:                    None

Appearance and Physical State:  blue liquid



Section 10 Stability and Reactivity

 
Chemical Stability:
              The product is stable under normal use conditions.

Conditions to Avoid:  
              Excessive heat, sunlight

Incompatibility (materials to avoid):
	Strong oxidizing agents, Reducing agents, Bases, Chromates


Hazardous Products of Deposition:
	In combustion, the material emits toxic fumes.




Section 11: Toxicological Information

 
Acute toxicity: Methylene Blue
	Oral, Rat LD50: 1180 mg/kg




Section 12: Ecological Information

None available from our selected sources.


Section 13: Disposal Considerations

Waste disposal:
Arrange for collection by an approved hauler, following federal, state
      and local regulations.

Another option, assuming it is legal to do so where you are located:
Mix or dissolve the material with a combustible material and burn in a
chemical incinerator equipped with afterburners and scrubbers.

Disposal of packaging:
Arrange for disposal following all federal, state, and local regulations.
      Clean first with water and the waste water should be discarded as a
      normal industrial waste,  following all federal, state and local
      rules and regulations.





Section 14: Transport Information


This product is not classified as dangerous.

DOT Hazard Class:      Non-Regulated

UN/NA ID:              Not Regulated

Packing Group:         Not Applicable

Labels:                Not Regulated


Marine Pollutant:      No

NAER Guidebook:        Not Regulated

DOT Status:            Not Regulated





Section 15: Regulatory Information

TSCA:
All components of this product are listed on the TSCA 8(b) inventory.  
If identified components of this product are listed under the TSCA
      12(b) Export Notification Rule, they will be listed below.

    TSCA 12(b) Component      Listed under TSCA Section


SARA-Section 313 Emissions Reporting:

    Component                 Reporting Threshold


SARA-Section 311/312:
   No components present in this product are subject to the reporting 
   requirements of this statute.


CERCLA Hazardous Substances and their Reportable Quantities:

    Component                 Reportable Quantity



California Prop. 65:
Proposition 65 requires manufacturers or distributors of consumer
      products into the State of California to provide a warning statement
      the product contains ingredients for which the State has found to
      cause cancer, birth defects or other reproductive harm.  If this
      product contains an ingredient listed by the State of California
      to cause cancer or reproductive toxicity, it will be listed below:

   No components are found in this product.

European/International Regulations
European Labeling in Accordance with EC Directives

Hazard Symbols:  Xn,i

Risk Phrases:
	R22  Harmful if swallowed
	R36/37/38 Irritating to eyes, respiratory system and skin

Safety Phrases:
	S22  Do not breathe dust
	S26  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
	S36/37/38 Wear suitable protective clothing, gloves and eye/face protection

Canada:
CAS# 7220-79-3 is not on Canada's DSL list.
CAS# 7732-18-5 is on Canada's DSL List.
CAS# 7220-79-3 is not on Canada's NDSL list.
CAS# 7220-79-3 has a WHMIS of D2B.





Section 16: Additional Information

Disclaimer of Liability:
Caution! Do not use SPI Supplies products or materials in applications involving implantation within the body; direct or indirect contact with the blood pathway; contact with bone, tissue, tissue fluid, or blood; or prolonged contact with mucous membranes. Products offered by SPI Supplies are not designed or manufactured for use in implantation in the human body or in contact with internal body fluids or tissues. SPI Supplies will not provide to customers making devices for such applications any notice, certification, or information necessary for such medical device use required by US FDA (Food and Drug Administration) regulation or any other statute. SPI Supplies and Structure Probe, Inc. make no representation, promise, express warranty or implied warranty concerning the suitability of these materials for use in implantation in the human body or in contact with internal body tissues of fluids.

*************************************************************************************

The information and recommendations set forth above are taken from sources believed to be accurate as of the date hereof, however SPI Supplies and Structure Probe, Inc. make no warranty with respect to the accuracy of the information or the suitability of the recommendations, and assume no liability to any user thereof. The information contained in this sheet does not constitute a hazard assessment and should not be used in place of the user's own assessment of work place risks as required by other health and safety legislation.

Be aware of the Structure Probe, Inc. Copyright Policy. Structure Probe, Inc. grants a nonexclusive license to make unlimited copies of this safety sheet for internal use only. Quite obviously, this information would pertain only to this material when purchased from SPI Supplies as product from other sources, with other ingredients and impurity levels could have substantially different properties.

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