Glycol methacrylate (GMA), otherwise known as 2-hydroxyethyl methacrylate,
is the embedment of choice for both TEM and LM applications, particularly
for hydrated specimens with sensitive "antigenic sites". The GMA monomer
is water white, has a viscosity that is actually slightly less than water,
and will infiltrate easier
than any other resin or monomer. It is especially popular with those
working on bone, cartilage, and difficult-to-infiltrate plant tissue.
The SPI-Chem Brand GMA monomer is supplied with the methacrylic acid
originally present substantially removed but with small amounts of
inhibitors present, to inhibit spontaneous polymerization during synthesis
and storage. This inhibitor need not be removed before use. The benzoyl
peroxide catalyst as supplied is provided in granular form.