Liposome Suspension by Anaglyphic Stereo

Freeze fracture and etching, then viewed by TEM

Sample was prepared by first rapid quenching using jet freezing techniques, followed by preparation by freeze fracture and teching, followed by transmission electron microscopy of the replica of the fractured surface. The difference in angular position was 0° and +2°.

In order to see the 3D stereo effect, it is necessary to have anaglyphic stereo glasses of the "red/cyan" type.

For best viewing of this analglyphic stereo image, and also, to more easily acclimate the eyes for this kind of viewing, we recommend a viewing distance, at least to start, of approximately 3 feet or 1 meter. After the eyes become acclimated, you can slowly come closer to the screen, moving to the right and left. If the stereo effect is "lost", then back up until it comes back and repeat.

This micrograph demonstrates many of the different features one is likely to see in actual liposome suspensions including unilamellar, bi-lamellar and even multilamellar structures.

Special note: Structure Probe, Inc., via our laboratory services, offer high quality freeze fracture TEM analytical services. Our experience spans a roughly ten year period doing these kinds of studies for clients on a contract or purchase order basis.

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